Edoardo Brizio, born in Turin by braid parents in 1846, was very interested in literature, science and archeology. Admitted as the only pupil at the Italian Archaeological School in Pompeii where for three years he was followed (albeit occasionally) by De Ruggiero and Fiorelli. The Pompeian period allowed the young Brizio to gather elements that were the basis of his first publications dedicated to the Pompeian monuments that were gradually discovering. These studies were due to the high humidity of the Pompeian site, the cause of a disease that forced him to leave the archaeological area of ​​Vesuvius to move to Rome where he investigated the Palatine in the company of Pietro Rosa. Thanks to the interest of Quintino Sella, in 1874, he was able to move to Greece to complete his archaeological studies. Back in Italy, not even thirty, he won the competition for the archeology chair at the University of Bologna where he was one of the precursors in a nascent scientific discipline: paletnology.

In Bologna, where he had colleagues Giosuè Carducci and Giovanni Pascoli, he produced much of his scientific work: he investigated in particular the territory of Certosa, Marzabotto and Bologna. It is to him, during a study of the links between the Villanova and Etruscan civilizations, the identification of the oriental origin of the prehistoric origin of the populations of the center of the peninsula. He was secretary of the Society of Homeland History, a member of the Germanic Archaeological Institute, the Academy of Lynx and the Stockholm Academy. He obtained his honorary degree from the University of Petersburg and the Superintendence on major excavations in Emilia, Umbria and Marche that were then started. He died 5 May 1907 during a university lecture on excavations of the Farneto cave.